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Nicotine Addiction : Dependence on tobacco products, leading to health risks like lung cancer and heart disease

Native Americans, colonists, and enslaved workers decorated pipes they made in the Chesapeake Bay region with distinctive pin-like indentations Source: Virginia Humanities, Virginia Indian Archive, Five Chesapeake Pipe Bowl Fragments Why didn't the London Company find laborers to grow tobacco from places other than England

Nicotine suppresses the immune system and minimizes inflammation

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Lyon, France: World Health Organization