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Clinically, both specific ferroptosis inhibitors (such as Ferrostatin-1) and traditional medicine components (such as Puerarin) have emerged as promising therapeutic candidates, showing cardioprotective effects in experimental models

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While dementia is more common with advanced age, it is not a normal part of aging

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In this framework, neutrophils act as both sensors of metabolic stress and effectors of ovarian, endometrial, and vascular dysfunction, placing them at the nexus of PCOS-associated immuno-metabolic dysregulation