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It is present in every cell of the body, where it provides potent antioxidant protection, supports detoxification, and modulates the immune system

These excess FFAs are delivered to the liver, where they contribute to hepatic triglyceride accumulation, a hallmark of steatosis, and create a pro-inflammatory environment that promotes progression toward fibrosis 9

The new GI burden from berberine is then easier to attribute and manage because it is the only new variable

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Rubartelli A, Bajetto A, Allavena G, Wollman E, Sitia R

The FDA also warns that non-FDA-approved drugs may be dangerous and contain unknown ingredients