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However, each of the four products can be oxidized to 3-ketosteroids with a concomitant double bond isomerization to give progesterone, 17-hydroxyprogesterone, androstenedione, and testosterone, respectively (Figure 7), and the alternative route to the sex hormones is named the delta4-pathway

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We will have more to say later in this paper about mitochondrial membranes and how they are altered in response to oxidative stress, specifically focusing on a potential role for the anionic lipid cardiolipin both in protecting the ATPase pumps from deuterium toxicity and in facilitating the removal of dysfunctional mitochondria through the action of amyloidogenic proteins

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