10.1038/nature13148 Nature 68 MaoX.ZhouH.JinW
Moreover, two main types of receptor-mediated mitophagy pathway have been classified as follows in brief: ubiquitin-independent mitophagy receptors, including BCL2-interacting protein 3 (BNIP3) (Quinsay et al., 2010), BCL2-interacting protein 3 like (NIX/BNIP3L) (Sandoval et al., 2008), FUN14 domain-containing 1 (FUNDC1) (Otsu et al., 2015), autophagy and beclin 1 regulator 1 (AMBRA1) (Strappazzon et al., 2015), FKBP prolyl isomerase 8 (FKBP8) (Wei et al., 2017), and NLR family member X1 (NLRX1) (Zhang et al., 2019)
Frontiers in Pharmacology, 11 , Article 1132
requires screening)
It has also been demonstrated to impair the uptake of essential amino acids by the transporter protein SLC38A2, thereby decreasing the cellular levels of these nutrients [175]
Molecular Medicine 24 (1): 59