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443 The mechanism underlying the peroxide selectivity by PerR relative to Fur remains incompletely understood, but replacement of E108 in 2 by Asp as found in PerRs to create E108D Bs Fur makes it sensitive to H 2 O 2

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Costea et al., 2018), each classified by a dominant genus: Bacteroides (Enterotype 1) and Prevotella (Enterotype 2) and a third Firmicutes dominant cluster with Ruminococcus (Enterotype 3) (Arumugam et al., 2011

Examinaremos seus mecanismos moleculares, os resultados de estudos clnicos e pr-clnicos, suas aplicaes potenciais, bem como as consideraes relativas segurana e regulamentao