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For per protocol analysis, women who receive less than 50% of the projected doses during pregnancy will not be included in the analyses, well acknowledging that the ensuing effect estimates may be biased and will certainly represent an effect higher than what can be achieved even in our well-resourced study setting

For athletes, this uncertainty is critical

Choline is the major precursor of betaine, and it is used by the kidneys to maintain water balance and by the liver as a source of methyl-groups for methionine formation

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It's the difference between meaningful fat loss and expensive placebo

and certain diabetes medicines such as metformin