at high doses, it overwhelms and glucuronidation/CYP2E1 take over) Bile acids Catecholamines (dopamine, norepinephrine, epinephrine) Cholesterol DHEA and steroid hormones Estrogens Minoxidil (requires sulfation for activation) Thyroid hormones Sulfation is not always detoxifying
Theres also some research into DSIPs potential in neuroprotective, anticonvulsive, and antinociceptive (pain reduction) effects
Pernicious anaemia is caused by a deficiency in vitamin B12, due to atrophic gastritis, an autoimmune condition where the immune system destroys self, in this case the parietal cells of the stomach
The downstream sequence past P1 is highly variable
doi:10.1006/cbir.2002.0861.
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