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Interestingly, a small trial in 30 premenopausal women found that daily multivitamin supplementation for ten weeks did not improve overall mood, but when the supplement also contained 7 mg/day of zinc (RDA=8 mg/day), the authors noted significant improvements in two components of POMS: the anger-hostility and the depression-dejection scores (140)

However, only one human study exists (for knee pain, not bone healing specifically)

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Modern devices offer dose increments as fine as 0.01 mL, and the dial mechanism provides tactile and visual confirmation of the selected dose

No human clinical trials have been published for either compound