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Reference: Pickart L, Vasquez-Soltero JM, Margolina A

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Role of 4-hydroxynonenal in epidermal growth factor receptor-mediated signaling in retinal pigment epithelial cells

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2.4 CHAC1-mediated regulation of stem cell fate and development via NOTCH1 signaling Given the central role of glutathione in maintaining redox balance, its levels are a key determinant of stem cell fate