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Last updated: March 22, 2026 Introduction to Ulcerative Colitis The principal causes of Ulcerative colitis are complex, with a weakened epithelial (gut) barrier function-AKA leaky gut being the hallmark of this and other autoimmune diseases
Franken DG, Boers GHJ, Blom HJ, and Trijbels JMF (1994)
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NICE obesity guidance (CG189) recommends multicomponent interventions addressing diet, physical activity, and behaviour change as first-line management