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Goc J, Germain C, Vo-Bourgais TKD, Lupo A, Klein C, Knockaert S, et al

Urolithins, ellagic acid-derived metabolites produced by human colonic microflora, exhibit estrogenic and antiestrogenic activities

This upregulation exhausts intracellular GSH, leading to ROS buildup and oxidative DNA damage that can ultimately generate TP53 mutations, a process that is halted when CHAC1 is knocked down (Wada et al., 2018)

Triglyceride, cholesterol, and free fatty acid content were determined using the Infinity Triglycerides reagent (Thermo Scientific), Infinity Cholesterol reagent (Thermo Scientific), and the free fatty acid quantification assay kit (Abcam), respectively, following the manufacturers instructions

It has even been shown that Glutathione can slow down the rate of brain tissue damage in those with Alzheimers disease