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PV2 and PV3 nanobody mutants with pAcF incorporated were purified and verified by SDS-PAGE and mass spectrometry to ensure correct insertion of the ncAA (Figures S3&4)

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Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons

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Deficiencies in L-Carnitine can increase fatigue and decrease recovery rate following physical activity.** A number of tissues contain significant concentrations of ALC but these decrease as we age and there is evidence that dietary supplementation can address these shortfalls.**

10.1021/tx0601408