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Description

Ferroptosis is characterized by iron accumulation, lipid peroxidation, depletion of glutathione (GSH), and inactivation of glutathione peroxidase 4 (GPX4) (12)

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Combining antiangiogenic agents, such as saikosaponin b2 which targets the VEGF/ERK/HIF-1 pathway, with immunotherapy enhances treatment efficacy

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Demirel, H

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41,42 Epigenetics and genetics Emerging evidence suggests that epigenetics (DNA methylation, histone acetylation/deacetylation and microRNA (miRNA) expression) may contribute to the pathophysiology of inflammatory processes

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