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italica ) inhibits formation of the anticancer agent sulforaphane

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Other studies have complemented the upstream of this signaling pathway and showed that sUA induces IR in HUA by activating the Nrf2/HO-1 signaling pathway through up-regulation of the regulatory thioredoxin-interacting protein (TXNIP) in macrophages that inhibits IRS2/PI3K/AKT signaling pathway (57)

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Disruption of the lung-gut-brain axis is responsible for cortex damage induced by pulmonary exposure to zinc oxide nanoparticles

3 Mitochondrial ROS induction underlies NE protection