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[DOI] [PubMed] [Google Scholar] 16.Roth E, Manhart N, Wessner B

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Cellular senescence is widely recognized as a key factor in the aging process, and it can be activated by factors such as oxidative stress, telomere shortening, and oncogene expression [198]

Together, these mechanisms converge to promote -Syn accumulation, exacerbate lysosomal dysfunction, and thus contribute to cell death in PD