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Vitamin B12 and Cobalt Allergy Cobalt is the central atom contained within a vitamin B12 molecule, which is why a cobalt allergy can trigger acne in the course of vitamin B12 therapy (6)

Some sources mention that while mainstream FDA approved for weight loss claims exist in marketing, regulatory status is ambiguous (i.e., not formally approved for broad weight-loss indication)

Use only in controlled research environments

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Injections may provide more predictable absorption, particularly for those with digestive or absorption difficulties

These occur in less than 2% of research participants