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Even though structural elements of the BBB are similar, there are molecular differences between animals and humans (O'Brown et al., 2018)

It affects chromatin structure and transcription accuracy through epigenetic modifications (Park et al., 2023)

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Whereafter, L-theanine could regulate the innate immunity of mice with immune stress induced by ETEC, mainly by inhibiting the overexpression of nucleotide-binding oligomerization domain, IL-1, and TNF-, partially reducing the protein level of NF-B p65, and suppressing the phosphorylation of ERK1/2 (96)