Occasional mild injection-site reactions (redness, itch) may occur with subcutaneous administration
Tirzepatide is the same active ingredient as Mounjaro and Zepbound
For dye-based DSF, SYPO Orange (Sigma-Aldrich) was used at a dilution of 1:1000 with a protein concentration 0.1 mg/mL in a final volume of 25 L
Doublecortin is a microtubule-associated protein produced during neurogenesis
Annu Rev Pharmacol Toxicol 43:23360 Dinkova-Kostova AT, Holtzclaw WD, Cole RN, Itoh K, Wakabayashi N, Katoh Y, Yamamoto M, Talalay P (2002) Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
HUBERMAN: Melanocyte-stimulating hormone has the effect of stimulating pigmentation of the skin by activating what are called melanocytes that exist within the skin