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Both the classes share number of conserved residues in the N-terminal GSH binding domain and possess a distinct structural feature of N-terminal extension (Theodoulou et al., 2003)

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From sulfur-rich cruciferous vegetables to protein sources that provide essential amino acids, nature offers abundant resources to enhance your master antioxidant systems

In fact, it is the main mediator of the so-called detoxification reactions, by which toxins are eliminated, both those produced by our body and those from outside, such as from drugs and food additives

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Under oxidative stress these three systems work in concert to detoxify ROS and lipid peroxides, maintain protein structure and function via thiol repair, prevent activation of redox-sensitive inflammatory pathways, and preserve mitochondrial membrane integrity and prevent apoptosis