GCLC can be cleaved by a caspase 3-dependent mechanism from the full-length 73 kDa to a 60 kDa form during apoptosis induced by TGF-1, TNF and -Fas [45,130]
Thus, promoting the proliferation, migration and differentiation of melanocytes is an effective method for repigmentation of vitiligo
10.1016/S0006-2952(03)00504-5 52
"Dual localization of glutathione S -transferase in the cytosol and mitochondria: implications in oxidative stress, toxicity and disease"
Walden [Tetrahedron Letters, 1985, vol
In the field of liver transplantation, IRI is a pivotal issue, triggering local inflammation and immune responses that could escalate into rejection, negatively impacting graft function and patient outcomes [195]