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Clinicians therefore need to know not only the half-life of the drug that they are prescribing but also what the half-life might be given the presence of one or more of these factors in the patient to whom the drug is being prescribed

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The mouse hemorrhagic liver model was established as follows: Balb/c mice were anesthetized and then fixed on the mouse operating bed

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These findings suggest that LPS may trigger ferroptosis in granulosa cells through a dual mechanism involving suppression of the antioxidant defense system (GPX4) and disruption of iron metabolic homeostasis (via SLC7A11-mediated cystine uptake and ferritin-mediated iron storage)