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However, when viral infection, environmental stress, or immunosuppression impairs these defenses, microbes from the oral cavity and URT can aberrantly colonize the LRT, markedly increasing the risk of BRD through pathogenic mechanisms and microbial agents similar to those described in the URT section above
This would have likely netted him another Nobel prize, but Watson and Crick beat him to it
10,22,23 These acute exacerbations are unequally distributed, with some patients exhibiting a frequent exacerbator phenotype, suffering from repetitive and severe exacerbations
In addition to ETC, other ROS production sites exist in mitochondria including monoamine oxidase (MAO) and p66shc