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By carefully controlling solvent composition and flow rate, researchers can optimize separation so that closely related impurities appear as distinct peaks rather than merging together

doi: 10.1016/j.pharmthera.2017.11.005 233 BangOYSaverJLLiebeskindDSPinedaSOvbiageleB

These drugs were promising early on, but many were abandoned for either failing to show clear benefits or for allegedly causing severe side effects

Estrogen and estrogen receptor--mediated transrepression of bile salt export pump

[158, 159] demonstrated that B-CQDs and cobalt-conjugated N-CQDs elicited no detectable oxidative stress, apoptotic signalling, or microglial activation within neuronal tissues [158, 159]

Structure, activation, and regulation of nox2: at the crossroad between the innate immunity and oxidative stress-mediated pathologies