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[19] [21] The duration of therapy depends on the indication and patient response
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Furthermore, the dysfunctional ETC produces more ROS due to incomplete oxygen reduction, damaging all kinds of mitochondrial proteins [129]
Traditional capsules often show bioavailability in the 2 to 10 percent range, meaning only a small fraction may reach circulation
Health concerns Most people dont need to supplement with vitamins and can get all they need from eating a healthy, balanced diet.12 However, some people can benefit from taking them, including, but not limited to: Pregnant individuals (and those who may become pregnant) should take 400mcg of folic acid each day (in addition to eating folate-rich foods) to prevent birth defects like anencephaly and spina bifida.13 Those with a malabsorption condition, such as celiac or ulcerative colitis, that increases the risk of various nutrient deficiencies, can benefit.14 People who dont get enough Vitamin D (which is extremely common) could benefit from supplementation.1 15 Individuals who eat a vegetarian or vegan diet are more likely to have B12 deficiencies, as the vitamin isnt found in plants.16 No matter the reason you may want to supplement with vitamins, its important to discuss it with your doctor before taking them to make sure theyre safe for you
microscopic colitis (7.4%)
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