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To determine oxidized proteins carbonyl groups were derivatized to 2,4-dinitrophenilhydrazone (DNP-hydrazone) by its reaction with 2,4-dinitrophenilhidrazine (DNPH)

Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11

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Further analysis revealed that male L-DKO livers had dramatically increased markers of apoptosis and oxidative DNA damage compared to female mice (Fig