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The result slower skin cell turnover, reduced collagen synthesis, weaker repair response to sun damage and environmental stress is what most people notice as the first signs of aging

The application of melatonin resulted in a decrease in the relative membrane-leakage rate and the inhibition of superoxide radicals (O 2 ), malondialdehyde (MDA) and hydrogen peroxide (H 2 O 2 ) production

[PubMed: 12485966] 664

Photostimulation of Phox2b medullary neurons activates cardiorespiratory function in conscious rats