[DOI] [PubMed] [Google Scholar] 29.Chang C-H, Tsai W-C, Hsu Y-H, Pang J-HS
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Zhu, Y., Chen, J., Zhang, J., Wang, F
In an in vitro model (human mesangial cells stimulated by Gd-IgA1), cell viability was markedly reduced, accompanied by lipid peroxidation and characteristic mitochondrial changes associated with ferroptosis
Specifically, hepatoma cells with low expression of GOT2 showed a high dependence on Gln metabolism by increasing Gln metabolism, nucleotide synthesis, and glutathione synthesis to support cellular antioxidants (Fig
CRISPR cas9-mediated deletion of biliverdin reductase A (BVRA) in mouse liver cells induces oxidative stress and lipid accumulation