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The subsequent sections elucidate methods for restoring the structural and functional BBB

MMPs are enzymes that break down the extracellular matrix necessary for remodeling damaged tissue, but problematic when elevated chronically

Bioconjugated manganese dioxide nanoparticles enhance chemotherapy response by priming tumor-associated macrophages toward M1-like phenotype and attenuating tumor hypoxia

doi: 10.1073/pnas.2008306117 37

Cellular Defense Peptides increase the function of native antioxidant enzymes like superoxide dismutase (SOD), catalase, and glutathione peroxidase by inducing expression or boosting enzyme stability

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