According to the NICE Clinical Knowledge Summary (CKS) and the British National Formulary (BNF) , the standard treatment for B12 deficiency without neurological symptoms involves: Hydroxocobalamin 1 mg intramuscularly three times weekly for two weeks Followed by maintenance doses of 1 mg every three months For patients with neurological symptoms (such as paraesthesia, numbness, cognitive changes, or gait disturbances), more intensive treatment is required: Hydroxocobalamin 1 mg intramuscularly on alternate days until no further improvement occurs Followed by 1 mg every two months for maintenance Pernicious anaemia , an autoimmune condition where the body cannot produce intrinsic factor, requires lifelong treatment
Each time the dose changes, you need to recalculate how many units to draw
Drug-Disease Interactions MECOVON 1000 INJECTION 1ML interacts with the following diseases: Kidney Disease: If you have kidney disease, your body may not metabolise and remove MECOVON 1000 INJECTION 1ML as efficiently, potentially affecting its effectiveness
doi:10.1016/S0014-2999(99)00486-0
Its good for patients with severe deficiencies or who need quick treatment
Draw your calculated dose into an insulin syringe, ensuring no air bubbles (gently tap syringe and push plunger to expel air)
