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However, while HFI 419 exerts a proven cognitive-enhancing effect in rodents after icv administration similar to that of Ang IV 1 and LVV-H7 3 , the Ki value of 420 nM seems not optimal

Hence, we reasoned that Cys uptake may counteract ferroptosis not only through the well-established CysGSHGPX4 axis but also by enabling biosynthesis of S 0 species