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At the same time, cigarette smoke impairs innate defense mechanisms by macrophages, epithelial cells, dendritic cells, and natural killer cells, thereby increasing the risk, severity, and duration of infection

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[31] He returned to play the role of Martin Riggs in Lethal Weapon (1987), a film which helped to cement his status as a Hollywood "leading man"

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Warning images Then came the 2000s, and with it, pictorial health warnings

Though the US Food and Drug Administration holds some ability to regulate tobacco and nicotine products from the 2009 Family Smoking Prevention and Tobacco Control Act, delays in the legal process have allowed tobacco companies to outpace lawmakers